|Division of Engineering & Applied Science | Division of Biology | Division of Chemistry & Chemical Engineering|
Professor of Environmental Microbiology Jared Leadbetter, Biology graduate student Elizabeth Ottesen, and their colleagues announce a new and efficient way of revealing guild-species relationships in complex microbial communities. The approach allows them to discover connections between bacterial cells from natural samples, and the activities encoded by genes. Read more... posted 11-30-2006
A new $4.4-million grant from the National Science Foundation will allow a research team, lead by Michael Dickinson, Zarem Professor of Bioengineering, to develop techniques to turn brain cells on and off in animals as they go about their daily activities, allowing the scientists to understand the details of how brain activity lead to complex behaviors. The five-year program is aimed at solving one of the remaining great challenges facing biologists---understanding the mechanistic basis of complex behavior. The work will focus on fruit flies, which are a powerful model system understood extremely well at the genetic level. Read the Caltech News Release. posted 10-6-2006
Reporting in the journal Lab on aChip, Professor Changhuei Yang and his coauthors describe a novel device that combines chip technology with microfluidics. Although similar in resolution and magnifying power to a conventional top-quality optical microscope, the optofluidic microscope chip is only the size of a quarter, and the entire device--imaging screen and all--will be about the size of an iPod. The new optofluidic microscope is one of the first major accomplishments to come out of Caltech's Center for Optofluidic Integration. Caltech News Release posted 9-5-2006
New results in this week's issue of Science from a team of biologists and engineers led by Mory Gharib, the Hans W. Liepmann Professor of Aronautics and Professor of Bio-Inspired Engineering, show that the embryonic vertebrate heart tube is a dynamic suction pump. In other words, blood flows by a dynamic suction action that arises from wave motions in the tube. The findings could lead to new treatments of certain heart diseases that arise from congenital defects. The lead author of the paper is Gharib's graduate student Arian Forouhar. According to Gharib, the new results show once and for all that "the embryonic heart doesn't work the way we were taught." Scott Fraser, the Anna L. Rosen Professor of Biology and Professor of Bioengineering, adds that the study shows the promise of advanced biological imaging techniques for the future of medicine. "The reason this mechanism of pumping has not been noticed in the heart tube is because of the limitations of imaging," he says. "But now we have a device that is 100 times faster than the old microscopes, allowing us to see things that previously would have been a blur. Now we can see the motion of blood and the motions of vascular walls at very high resolutions." Caltech News Release posted 5-4-2006
The ASCIT Teaching Awards were recently announced, with professor Niles Pierce among those honored for their exceptional teaching. Kudos!
Chin-Lin Guo has recently joined the Division as Assistant Professor of Bioengineering and Applied Physics. His research interests focus on modeling collective cellular and molecular behavior.
Building on years of research on the way that blood flows through the heart valves, Mory Gharib, Liepmann Professor of Aeronautics and Bioengineering, and his colleagues have devised a new index for cardiac health based on a simple ultrasound test. The index provides a new diagnostic tool for cardiologists in searching for the very early signs of certain heart diseases. The researchers show how ultrasound imaging can be used to create an extremely detailed picture of the jet of blood as it squirts through the cardiac left ventricle. Previous work by the Caltech team members has shown that there is an ideal length-to-diameter ratio for jets of fluid passing through valves, which means that any variation from this ratio is indicative of a heart that pumping in an abnormal manner. Caltech News Release posted 4-10-2006
Mory Gharib, Hans W. Liepmann Professor of Aeronautics and Bioengineering, has been elected a Fellow of the American Institute for Medical and Biological Engineering (AIMBE) in recognition of his many distinguished contributions to the field as well as his involvement with critical issues affecting medical and biological engineering.
|last update: 01/17/2013|